Secondhand cannabis smoke: what gets into your body?
NCT ID NCT06030674
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at how secondhand cannabis smoke affects healthy nonsmokers. Researchers will measure cannabis byproducts in urine before and after exposure in public places. The goal is to understand how much of the smoke's chemicals enter the body. This is a small pilot study with 200 participants.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- secondhand cannabis smoke exposure
- What this could lead to
- If successful, this could help understand how secondhand cannabis smoke enters the body and inform public health guidelines.
- What could go wrong
- This is a small, early pilot study with only 200 healthy nonsmokers, so results may not apply to everyone. The exposure happens in real-world settings, making it hard to control all factors.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 200 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Sep 2023
- Expected to finish
-
Jun 2027
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
21 to 50 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: \- Adult nonsmokers, aged 21-50, who: * Are healthy on the basis of medical history * Have systolic blood pressure \<150 * Have diastolic blood pressure \<100 * Have BMI between 18.1 and 34.9 * Able to perform moderate exercise, * Are not exposed to tobacco or cannabis SHS in their daily lives. (Nonsmoking status and low SHS exposure are determined by self-report on the screening questionnaire, salivary cotinine \< 10 ng/ml and THC \< 50 ng/m and exhaled CO2 below 4 ppm) Exclusion Criteria: * Current use of cannabis products, including CBD and edible THC products * Regular exposure to secondhand tobacco or cannabis smoke * Positive SARS-CoV-2 antibody test * Age 18 \< or \> 50 * Physician diagnosis of asthma, heart disease, hypertension, thyroid disease, diabetes, renal or liver impairment or glaucoma. * Unstable psychiatric condition (such as current major depression, history of schizophrenia or bipolar disorder) or current use of more than two psychiatric medications * Systolic blood pressure \> 150 * Diastolic blood pressure \> 100 * Pregnancy or breastfeeding (by urine hCG and/or history) * Alcohol or illicit drug dependence within the past 5 years * BMI \> 35 and \< 18 * Current illicit drug use (by history or urine test) * More than 1 pack year smoking history * Ever a daily marijuana smoker * Smoked anything within the last 2 months * Occupational exposure to smoke, dusts OR fumes * Concurrent participation in another clinical trial * Unable to communicate in English * No social security number
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Healthy are added.
Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Zuckerberg San Francisco General Hospital
RECRUITINGSan Francisco, California, 94110, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a protein powder with creatine and fiber boost everyday Well-Being?
- Green tech or hidden stress? bus Drivers' hearts monitored behind the wheel
- Shout it out: can growls and screams raise pain tolerance?
- Scientists probe why brain stimulation works for some and not others
- Tiny doses, big questions: how does the body handle this prodrug?
- First human test of CM583: can this biologic pass the safety check?