Laser showdown: which treatment best zaps sebaceous bumps?
NCT ID NCT04429607
First seen Jul 01, 2026 · Last updated Jul 02, 2026 · Updated 1 time
Summary
This study tests three different treatments for sebaceous hyperplasia—small, benign bumps on the skin. Participants receive either a combination of pulsed dye laser and Nd:YAG laser, an erbium:YAG laser, or a procedure called electrodesiccation and curettage. Each bump is treated twice, and researchers measure changes in size and number of bumps after 4 to 12 weeks. The goal is to find out which approach works best.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Laser (PDL, Nd:YAG, Erbium:YAG) and electrodesiccation with curettage
- What this could lead to
- If successful, this study could identify the most effective laser or procedure for removing or shrinking sebaceous hyperplasia lesions with minimal side effects.
- What could go wrong
- This is a small pilot study with only 18 participants, so results may not apply to everyone. Treatments may cause scarring or incomplete removal.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
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About 18 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2025
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. ≥18 years of age 2. Receiving cosmetic treatment for sebaceous hyperplasia 3. In good general health as assessed by the investigator 4. Participants must have the ability to understand and the willingness to sign a written informed consent prior to registration on study Exclusion Criteria: 1. Patient pregnant or nursing 2. Patient with history of poor wound healing that would result in hypertrophic scar or keloid at the discretion of the physician 3. Patient with recent sun exposure that would result in pigment changes at the discretion of the physician 4. Subject unwilling to sign an IRB approved consent form 5. Participants who are unable to communicate or cooperate with the investigator due to language problems, poor mental development, or impaired cerebral function are not eligible
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Northwestern University Department of Dermatology
Chicago, Illinois, 60611, United States
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