Lung cancer pilot: High-Dose radiation before surgery tested
NCT ID NCT03348748
First seen Nov 01, 2025 · Last updated Jun 21, 2026 · Updated 35 times
Summary
This early-phase pilot study looked at combining stereotactic body radiation therapy (SBRT) with surgery for patients with stage I-IIIA non-small cell lung cancer. SBRT delivers very high, precise radiation doses to the tumor while sparing healthy tissue. The study aimed to check safety and side effects, but it was terminated early with only 20 participants planned.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Roswell Park Cancer Institute
Buffalo, New York, 14263, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Stereotactic body radiation therapy (SBRT)
What this could lead to
If successful, this approach could show that giving a precise, high-dose radiation before surgery is safe and may improve outcomes for lung cancer patients.
What could go wrong
This was a very early, small pilot study that was terminated, so results are limited. The combination may not prove safer or more effective than standard treatment.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.