Lung cancer pilot: High-Dose radiation before surgery tested
NCT ID NCT03348748
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase pilot study looked at combining stereotactic body radiation therapy (SBRT) with surgery for patients with stage I-IIIA non-small cell lung cancer. SBRT delivers very high, precise radiation doses to the tumor while sparing healthy tissue. The study aimed to check safety and side effects, but it was terminated early with only 20 participants planned.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Stereotactic body radiation therapy (SBRT)
- What this could lead to
- If successful, this approach could show that giving a precise, high-dose radiation before surgery is safe and may improve outcomes for lung cancer patients.
- What could go wrong
- This was a very early, small pilot study that was terminated, so results are limited. The combination may not prove safer or more effective than standard treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Roswell Park Cancer Institute
Buffalo, New York, 14263, United States
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