Scientists probe immune cells to unlock secrets of sarcoidosis and TB
NCT ID NCT05916638
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how certain immune cells (monocytes and macrophages) behave in sarcoidosis and tuberculosis. Researchers will compare blood and tissue samples from 100 adults to find patterns that explain why these cells stay overactive in sarcoidosis. The goal is to better understand the disease and possibly discover new treatment ideas.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2024
- Expected to finish
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Jan 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult patients diagnosed with sarcoidosis or tuberculosis
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria: 1. Male and female \> 18 years old 2. Diagnosis of sarcoidosis and of tuberculosis 3. Affiliated to medical insurance Exclusion criteria: 1. HIV infection 2. pregnant or breastfeeding woman 3. Patient under legal protection, guardianship or curators 4. Absence of signed consent" Secondary exclusion criteria Other causes of granulomatosis ultimately identified as sarcoidosis or tuberculosis
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hôpital Bichat
RECRUITINGParis, 75018, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a Once-Daily HIV pill with food match Twice-Daily dosing during TB treatment?
- Can simple sputum and urine tests catch tuberculosis earlier?
- Can a common virus be turned into a TB vaccine? scientists test VIR-1778
- Fish oil meets TB drugs: can Omega-3 help clear infection faster?
- Can starting TB treatment immediately save lives in HIV sepsis?