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Saliva swab could revolutionize ovarian cancer diagnosis

NCT ID NCT05514028

First seen Apr 06, 2026 · Last updated Jun 23, 2026 · Updated 11 times

Summary

This study is testing whether RNA found in saliva can help doctors tell the difference between benign ovarian cysts, borderline tumors, and ovarian cancer. Researchers are collecting saliva samples from 746 women before and after surgery to see if a simple, non-invasive test could speed up diagnosis and improve care. The goal is to make the diagnostic process faster and less invasive for patients.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CGFL

    Dijon, Côte d'Or, 21079, France

  • CH Bastia

    Bastia, 20600, France

  • CH Niort

    Niort, 79021, France

  • CHP St Grégoire

    Saint-Grégoire, Ille Et Villaine, 35760, France

  • CHRU Bretonneau-Tours

    Tours, 37044, France

  • CHU Angers

    Angers, 49933, France

  • CHU Lyon Sud / Hospices Civils de Lyon

    Lyon, 69000, France

  • CHU Rennes

    Rennes, 35000, France

  • CHU Rouen, Hôpital de Bois-Guillaume

    Rouen, France

  • CHU Strasbourg

    Strasbourg, Haut-Rhin, 67200, France

  • CHU Tenon

    Paris, 75020, France

  • CHU Toulouse

    Toulouse, Haute-Garonne, 31059, France

  • CHU de Caen

    Caen, Calvados, 14000, France

  • Centre Antoine Lacassagne

    Nice, France

  • Centre de Maternité et de Néonatologie Wassila Bourguiba

    Tunis, 01007, Tunisia

  • Clinique La sagesse

    Rennes, France

  • Clinique Pasteur

    Toulouse, France

  • Hôpital BICETRE

    Le Kremlin-Bicêtre, Val de Marne, 94275, France

  • Institut Bergonié

    Bordeaux, Gironde, 33076, France

  • Institut Gustave Roussy

    Villejuif, Val de Marne, 94805, France

  • Universitätsklinik für Frauenheilkunde

    Bern, 03010, Switzerland

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to a simple saliva test that speeds up ovarian cancer diagnosis and improves patient care.

What could go wrong

This is an observational study, not a treatment trial. The test may not prove accurate enough for routine use, and results are still early.

Conditions

The condition(s) this trial relates to.

neoplasm ovarian cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.