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Spit test could spot ovarian cancer earlier

NCT ID NCT05514028

Ongoing Diagnosis Sponsor: ZIWIG Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether RNA in saliva can help tell the difference between ovarian cancer, borderline tumors, and benign cysts. Researchers are collecting saliva samples from 746 women before and after surgery. The goal is to find a simple, non-invasive way to speed up diagnosis and improve care for women with ovarian masses.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could lead to a simple saliva test to quickly identify ovarian cancer, reducing diagnosis time and improving treatment pathways.
What could go wrong
This is an observational study, not a treatment trial. The test may not prove accurate enough for clinical use, and results are still early.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

borderline epithelial tumor of ovary neoplasm ovarian cancer ovarian cyst

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BORDERLINE OVARIAN CANCER OVARIAN CANCER OVARIAN CYST BENIGN

Contacts and locations

Locations

  • CGFL

    Dijon, Côte d'Or, 21079, France

  • CH Bastia

    Bastia, 20600, France

  • CH Niort

    Niort, 79021, France

  • CHP St Grégoire

    Saint-Grégoire, Ille Et Villaine, 35760, France

  • CHRU Bretonneau-Tours

    Tours, 37044, France

  • CHU Angers

    Angers, 49933, France

  • CHU Lyon Sud / Hospices Civils de Lyon

    Lyon, 69000, France

  • CHU Rennes

    Rennes, 35000, France

  • CHU Rouen, Hôpital de Bois-Guillaume

    Rouen, France

  • CHU Strasbourg

    Strasbourg, Haut-Rhin, 67200, France

  • CHU Tenon

    Paris, 75020, France

  • CHU Toulouse

    Toulouse, Haute-Garonne, 31059, France

  • CHU de Caen

    Caen, Calvados, 14000, France

  • Centre Antoine Lacassagne

    Nice, France

  • Centre de Maternité et de Néonatologie Wassila Bourguiba

    Tunis, 01007, Tunisia

  • Clinique La sagesse

    Rennes, France

  • Clinique Pasteur

    Toulouse, France

  • Hôpital BICETRE

    Le Kremlin-Bicêtre, Val de Marne, 94275, France

  • Institut Bergonié

    Bordeaux, Gironde, 33076, France

  • Institut Gustave Roussy

    Villejuif, Val de Marne, 94805, France

  • Universitätsklinik für Frauenheilkunde

    Bern, 03010, Switzerland

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