Chest tube clogging: does heparin help?
NCT ID NCT06314620
First seen Jun 27, 2026 · Last updated Sep 16, 2026 · Updated 2 times
Summary
This study looks at two methods to prevent small chest tubes from getting blocked in patients with pleural effusion (fluid around the lungs). One method uses only saltwater flushes, the other adds a heparin lock. The goal is to see which keeps the tube working longer. About 40 adults in a hospital in Malaysia will take part.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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40 people
The number who actually took part.
- Started
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Mar 2024
- Finished
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Sep 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: • All patients admitted in medical wards for pleural effusion who had small bore intercostal catheters inserted. Exclusion Criteria: * Patients with hydropneumothorax with small bore intercostal catheters * Patients with septated effusion planned for intrapleural fibrinolysis * Patients with severe coagulopathy * INR ≥ 1.5 * PT \> 37s * aPTT \> 100s * Patients with thrombocytopenia of less than 50 x 109/L * Patients who has not consented to be involved in the study * Patients with indwelling pleural catheters * Unconscious patients will be excluded from this study * Patients with poor GCS score will be excluded from this study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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National University of Malaysia
Kuala Lumpur, Kuala Lumpur, 53300, Malaysia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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