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Asthma drug tested for breathing machine patients

NCT ID NCT01958814

Symptom relief Sponsor: University Hospital, Tours Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether giving the drug salbutamol (often used in asthma inhalers) through a nebulizer helps people with severe COPD who are having a flare-up and need a breathing machine. The trial included 43 adults and compared the drug to a placebo. The main goal was to see if it improved lung function and breathing symptoms.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

43 people

The number who actually took part.

Start date

Feb 2012

Finished

Jul 2015

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patient over 18 years old * Patient with BPCO, defined: * by an irreversible obstructive syndrome * and\\or by different arguments (histories, symptoms, physical examination, thoracic radiography, gas of the blood) * Decompensation of this BPCO in the form of acute respiratory failure * No argument for a dominant acute left cardiac insufficiency * Consent signed by the patient * Patient with national health assurance Exclusion Criteria: * Contraindications in the not invasive ventilation * Patient not volunteer for the realization of the spirometry * Precautions for use of ß2 mimetic (engrave hyperthyroidism) * Under guardianship patient or protection of justice * Pregnant patient

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Conditions

The condition(s) this trial relates to.

acute respiratory failure chronic obstructive pulmonary disease respiratory failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic respiratory failure

Contacts and locations

Locations

  • CHRU de Tours

    Tours, 37000, France

  • Service de Réanimation

    Poitiers, 86000, France

  • Service de Réanimation Médicale - CHR d'Orléans

    Orléans, 45000, France

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