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Can a 2-Week program cut HIV and violence among teen boys?

NCT ID NCT06750107

Prevention Sponsor: Brown University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed Phase 3 trial tested a program called Safe South Africa, designed for teenage boys aged 15-17 in high-risk South African communities. The program includes two weekly group sessions and home activities to reduce HIV risk behaviors and intimate partner violence. Researchers measured new HIV and STI infections, acts of violence, and attitudes supporting violence. The goal is to find a practical way to improve health and safety for young people.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Safe South Africa behavioral intervention (2-week group sessions with take-home activities)
What this could lead to
If effective, this program could provide a scalable way to reduce HIV infections and violence among teenage boys in high-risk communities.
What could go wrong
This is a completed trial, but results are not yet published. The intervention is short (2 weeks) and relies on self-reported behavior, which may not reflect real-world impact.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

836 people

The number who actually took part.

Started

Jan 2025

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

15 to 17 years

Sex

Male participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * identification as boys * ages 15-17 years * enrolled at public high schools in South Africa situated in communities with high rates of HIV and violence Exclusion Criteria: * does not have written parental consent * does not have written assent

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Conditions

The condition(s) this trial relates to.

HIV infectious disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Control Intervention

Contacts and locations

Locations

  • Schools in Cape Town area

    Cape Town, South Africa

More trials for these conditions

Other studies related to the condition(s) this trial covers.