New drug targets aggressive brain tumors in phase II trial
NCT ID NCT04559230
First seen Apr 02, 2026 · Last updated Jun 17, 2026 · Updated 10 times
Summary
This study tests a drug called sacituzumab govitecan in 32 adults whose glioblastoma (a type of brain cancer) has returned after standard treatment. The drug targets a protein called Trop-2 found on tumor cells. The main goal is to see if patients live longer compared to past results with the older drug lomustine.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cleveland Clinic Taussig Cancer Center
RECRUITINGCleveland, Ohio, 44106, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Texas Oncology Austin
RECRUITINGAustin, Texas, 78705, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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University of Texas Health Science Center San Antonio at the Cancer Therapy and Research Center
RECRUITINGSan Antonio, Texas, 78229, United States
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.