Blood test may speed up epilepsy diagnosis in ER
NCT ID NCT07527754
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether measuring a protein called S100B in the blood can help emergency doctors quickly tell if a person's fainting spell was caused by epilepsy or something else, like a heart problem. About 100 adults who come to the ER after losing consciousness will give an extra blood sample. Their final diagnosis will be checked three months later to see how accurate the S100B test is.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Apr 2026
An estimate. Start dates often move.
- Expected to finish
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Jul 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population will consist of adult patients presenting to the Emergency Department of Henri Mondor University Hospital during the inclusion period for an episode of transient loss of consciousness. Eligible patients will be screened consecutively and included if they meet all predefined inclusion criteria and none of the exclusion criteria.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * • Adult ≥ 18 years old * Presentation to the Emergency Department of Henri Mondor University Hospital * History of loss of consciousness * Undergoing a blood test as part of Emergency Department care * Covered by social security * Has agreed to participate in the study Exclusion Criteria: * Symptoms occurring more than 12 hours ago * History of head trauma without brain imaging performed * History of head trauma with intracranial bleeding confirmed on brain imaging * Refusal to participate in the study * Pregnant and/or breastfeeding women * Individuals unable to provide consent, particularly due to cognitive impairment * Individuals under legal protection: * Placed under guardianship * Deprived of liberty (incarcerated or hospitalized without consent)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hôpital Henri Mondor
Créteil, Île-de-France Region, 94000, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Reading the Brain's signals to predict who benefits from deep brain stimulation
- Can a Comfort-Focused education program improve life with epilepsy?
- Can video games rewire young brains after injury?
- High-Fat Diet's effect on epilepsy: scientists track brain signals
- Epilepsy drug candidate put to the test in healthy volunteers