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Shocking new hope for stroke survivors: brain zaps plus rehab may restore movement

NCT ID NCT07369648

Symptom relief Sponsor: Hanoi Medical University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 18, 2026 · Updated 2 times

Summary

This study tests whether adding a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) to standard physical therapy can improve arm and hand function in people who have had a first ischemic stroke. Sixty-six adults aged 18 to 80 with moderate weakness on one side will receive either real or sham rTMS combined with motor rehabilitation. Researchers will measure changes in movement, balance, daily activities, and quality of life over six months.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 66 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2026

Expected to finish

Dec 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged 18 to 80 years. * Diagnosed with a first-ever ischemic stroke, confirmed by neuroimaging. * Presence of unilateral hemiparesis attributable to the first-ever ischemic stroke. * Time since stroke onset: * Acute stage: \< 1 month after stroke onset * Subacute stage: 1 to 6 months after stroke onset * Chronic stage: \> 6 months after stroke onset * Moderate neurological impairment, defined as a baseline NIHSS score between 5 and 14. * Cognitive ability sufficient to understand and follow instructions, indicated by a baseline MMSE score ≥ 20. * Medically stable and able to participate in a structured motor rehabilitation program. * Provided written informed consent prior to study enrollment. * NIHSS and MMSE scores are assessed at baseline only to characterize neurological severity and cognitive status at study entry Exclusion Criteria: * Motor impairment caused by conditions other than ischemic stroke, such as musculoskeletal disorders, traumatic brain injury, Parkinson's disease, encephalitis, or other neurological conditions. * Contraindications to repetitive transcranial magnetic stimulation, including but not limited to intracranial metallic implants, implanted electronic medical devices (e.g., pacemaker), cochlear implants, known bleeding disorders, pregnancy, history of epilepsy or seizure disorders, severe cardiac disease, severe psychiatric or neurological disorders interfering with participation, or active skin conditions at the stimulation site. * History of epilepsy or seizure disorders. * Recurrent stroke occurring during the intervention period. * Refusal to participate, withdrawal of informed consent, or non-adherence to the intervention protocol.

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Conditions

The condition(s) this trial relates to.

hemiplegia ischemic stroke

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hemiplegia Ischemic stroke Motor function impairment

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • Hanoi Rehabilitation Hospital

    RECRUITING

    Hanoi, Vietnam

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