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Could a magnetic helmet boost brainpower in Parkinson's?

NCT ID NCT03836950

Symptom relief Sponsor: VA Office of Research and Development Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a non-invasive brain stimulation technique called rTMS can safely improve mild thinking problems in veterans with Parkinson's disease. Researchers will give real or fake rTMS sessions to 56 veterans and measure changes in executive function (like planning and memory). The goal is to see if this approach is feasible and effective for cognitive rehabilitation.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
repetitive transcranial magnetic stimulation (rTMS) device
What this could lead to
If it works, this could offer a non-drug way to ease thinking problems in people with Parkinson's disease.
What could go wrong
This is an early phase trial with only 56 participants, so results may not apply widely. The treatment is still experimental and may not improve thinking.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 1/2

Runs two stages together: safety and dose first, then whether the treatment works.

Participants

About 56 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2020

Expected to finish

Mar 2028

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a US federal agency other than the NIH.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Veterans who seek services at Hines VA Hospital or Jesse Brown VA Medical Center * Diagnosis of PD or atypical parkinsonism as determined by a neurologist * Meet criteria for having mild cognitive impairment * Receiving stable (i.e., no changes in medication and medication dose) medication and who are expected to remain on stable medication for the duration of the RCT * Speak and read English * 50 years or older Exclusion Criteria: * Dementia * Failure to demonstrate decision making capacity * History of deep brain stimulation surgery * Severe depression * Resting head tremor * Dyskinesia that will interfere with collecting imaging data * Has congestive heart failure * Implanted cardiac pacemaker or defibrillator * Cochlear implant, nerve stimulator, or intracranial metal clips * Implanted medical pump * Increased intracranial pressure * History of claustrophobia * Metal in eyes/face, shrapnel/bullet remnants in brain * Participants at potential increased risk of seizure including those who have the following: * history (or family history) of seizure or epilepsy * history of stroke, head injury, or unexplained seizures * presence of other neurological disease that may be associated with an altered seizure threshold * such as CVA, cerebral aneurysm, dementia, increased intracranial pressure * Concurrent medication use such as tricyclic antidepressants, neuroleptic medications, any other drug known to lower seizure threshold * Secondary conditions that may significantly alter electrolyte balance or lower seizure threshold * No quantifiable motor threshold such that rTMS dosage cannot be accurately deter-mined

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Mild cognitive impairment Parkinson's disease

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Edward Hines Jr. VA Hospital, Hines, IL

    RECRUITING

    Hines, Illinois, 60141-3030, United States

  • Jesse Brown VA Medical Center, Chicago, IL

    NOT_YET_RECRUITING

    Chicago, Illinois, 60612, United States

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