Can a magnetic helmet slow Alzheimer's? new trial aims to find out
NCT ID NCT07324161
First seen Jun 26, 2026 · Last updated Sep 01, 2026 · Updated 3 times
Summary
This study tests whether a non-invasive magnetic brain stimulation technique (rTMS) can improve thinking and memory in people with mild-to-moderate Alzheimer's disease. Researchers will also use brain scans to see if the treatment helps clear waste from the brain. The trial involves 66 participants who will receive either real or sham stimulation daily for two weeks, followed by weekly sessions for six months.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- repetitive transcranial magnetic stimulation (rTMS) device
- What this could lead to
- If it works, this could point toward a non-drug way to slow cognitive decline in Alzheimer's disease.
- What could go wrong
- This is a small, early-stage trial with only 66 participants. The treatment is not a cure, and benefits may be modest or not last long.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 81 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2025
- Expected to finish
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Apr 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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50 to 90 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Meets the 2018 NIA-AA diagnostic criteria for Alzheimer's disease (AD) * Meets DSM-5 diagnostic criteria * Mild to moderate disease severity (CDR Global Score 1 to 2) * Evidence of AD pathology: positive amyloid PET OR positive cerebrospinal fluid (CSF) AD biomarkers OR positive plasma AD biomarkers Exclusion Criteria: * Contraindications to rTMS treatment * Severe complications or immune diseases * Unable to cooperate with study procedures * History of epilepsy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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rTMS
RECRUITINGFuzhou, Fujian, 350001, China
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