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New mRNA vaccine targets RSV and hMPV in one shot

NCT ID NCT06237296

First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 33 times

Summary

This early-stage trial tested an experimental mRNA vaccine designed to protect against two respiratory viruses: RSV and hMPV. About 558 healthy adults aged 18 to 49 and 60 years or older received one injection of the vaccine at different doses. The main goals were to check safety and measure the immune response. The study is now complete.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Advanced Clinical Research- Site Number : 8400005

    Meridian, Idaho, 83642, United States

  • Charlottesville Medical Research Center Winding River - Site Number : 8400002

    Charlottesville, Virginia, 22911, United States

  • Coastal Carolina Research Center- Site Number : 8400001

    North Charleston, South Carolina, 29405, United States

  • Investigational Site Number : 0360001

    Camberwell, Victoria, 3124, Australia

  • Investigational Site Number : 0360002

    Botany, New South Wales, 2019, Australia

  • Investigational Site Number : 0360003

    Kanwal, New South Wales, 2259, Australia

  • Investigational Site Number : 0360004

    Sydney, New South Wales, 2035, Australia

  • Investigational Site Number : 0360005

    Morayfield, Queensland, 4506, Australia

  • Investigational Site Number : 0360006

    Blacktown, New South Wales, 2148, Australia

  • Investigational Site Number : 0360007

    Canberra, 2617, Australia

  • Investigational Site Number : 0360008

    Herston, Queensland, 4006, Australia

  • Meridian Clinical Research- Site Number : 8400007

    Binghamton, New York, 13905, United States

  • Velocity Clinical Research, Sioux City Site Number : 8400017

    Sioux City, Iowa, 51106, United States

  • Velocity Clinical Research- New Orleans Site Number : 8400016

    New Orleans, Louisiana, 70119, United States

  • Velocity Clinical Research- Site Number : 8400012

    Cleveland, Ohio, 44122, United States

  • Velocity Clinical Research-Hallandale Beach- Site Number : 8400013

    Hallandale, Florida, 33009, United States

  • Velocity Gardena Site Number : 8400011

    Gardena, California, 90247, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

RSV/hMPV mRNA vaccine

What this could lead to

If successful, this could lead to a single vaccine that protects against two common respiratory viruses (RSV and hMPV) in older adults.

What could go wrong

This is an early Phase 1 trial focused on safety and immune response, not yet on preventing illness. The vaccine may not produce strong enough immunity or could cause side effects. Results may not apply to the general population.

Conditions

The condition(s) this trial relates to.

respiratory syncytial virus infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.