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New dental tools aim to make root canals less painful

NCT ID NCT07642596

Symptom relief Sponsor: BUSRA OZTURK Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether using different nickel-titanium file systems, alone or with an XP-Endo Finisher irrigation device, can reduce pain after root canal treatment. Eighty adults with infected molars will be randomly assigned to one of four groups. Pain levels will be recorded over a week using a standard pain scale.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Nickel-titanium file systems (FKG Race Evo and One Reci) and XP-Endo Finisher irrigation device
What this could lead to
If successful, this could point to a way to reduce pain after root canal treatment by using better cleaning tools.
What could go wrong
This is a small, early-stage study with only 80 people, so results may not apply to everyone. Pain is subjective and hard to measure precisely.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 80 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2026

Expected to finish

Apr 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18-65 years. Healthy volunteers. Mandibular molar teeth with pulpal necrosis, asymptomatic status, chronic apical periodontitis, and periapical radiolucent lesion. Written informed consent. Exclusion Criteria: * Patients who have taken analgesic or anti-inflammatory drugs within the last 12 hours. Patients with allergy to non-steroidal anti-inflammatory drugs or local anesthetics. Pregnant or lactating patients. Patients with a history of gastrointestinal diseases. Patients using opioid medications. Teeth with calcified canals, resorptive defects, or complex root canal anatomy. Patients with severe periodontal disease. Patients with acute or chronic apical abscess or signs of systemic infection. Immunosuppressed patients.

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Conditions

The condition(s) this trial relates to.

chronic apical periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Postoperative pain after endodontic treatment

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Eskişehir Osmangazi University

    RECRUITING

    Eskişehir, Odunpazarı, 26040, Turkey (Türkiye)

  • Eskişehir Osmangazi University

    RECRUITING

    Eskişehir, Odunpazarı, 26040, Turkey (Türkiye)

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