New drug combo aims to rebuild bone in spinal cord injury patients
NCT ID NCT04232657
First seen Apr 26, 2026 · Last updated Jun 19, 2026 · Updated 10 times
Summary
This study tests whether a two-step drug treatment can improve bone density in people with long-term spinal cord injury who have bone loss. Participants receive either romosozumab (a bone-building drug) or a placebo for 12 months, followed by denosumab (a bone-strengthening drug) for another 12 months. The goal is to see if this approach can safely increase bone mass and reduce fracture risk.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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James J. Peters VA Medical Center, Bronx, NY
The Bronx, New York, 10468-3904, United States
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Kessler Institute for Rehabilitation
West Orange, New Jersey, 07052, United States
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.