New drug combo aims to strengthen bones in young women with period loss
NCT ID NCT06533865
First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 26 times
Summary
This study tests whether adding romosozumab to standard estrogen therapy improves bone density in girls and women aged 14-30 who have stopped menstruating due to intense exercise, stress, or an eating disorder. Participants receive either romosozumab or a placebo for 6 months, plus estrogen patches and progesterone pills, followed by a single dose of zoledronate. The goal is to see if the combination leads to stronger bones compared to placebo, with results measured at 6 and 12 months.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
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University of Virginia Medical Center
RECRUITINGCharlottesville, Virginia, 22903, United States
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