Lifting weights, not rest: new study tests exercise as treatment for lost periods
NCT ID NCT07612735
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether an 8-week supervised weightlifting program can help active women with functional hypothalamic amenorrhea (a condition where periods stop due to stress and low calorie intake) safely regain their menstrual cycles. Researchers will compare 28 women—some with the condition and some with normal cycles—tracking changes in strength, mood, and overall health. The goal is to offer an alternative to the usual advice of complete rest, which can be stressful for active women.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 28 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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May 2026
An estimate. Start dates often move.
- Expected to finish
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Jul 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * General Profile: Active women aged 18 to 35 years. * FHA Group: Clinical diagnosis of Functional Hypothalamic Amenorrhea, defined as the absence of menstruation for at least three consecutive months not attributable to other endocrine disorders. * Control Group (EU): Eumenorrheic women with regular ovulatory cycles lasting between 24 and 35 days during the previous six months. * Commitment: Agreement to participate in a supervised 8-week resistance training program and provision of medical documentation confirming menstrual status. Exclusion Criteria: * Hormonal Status: Current use of any hormonal contraceptives. * Medical Conditions: Diagnosed endocrine disorders such as Polycystic Ovary Syndrome (PCOS), hyperandrogenism, or thyroid dysfunction. Pregnancy: Current pregnancy. * Physical Activity History: Engagement in any structured resistance training program during the three months prior to the start of the intervention. * General Health: Any medical condition that could interfere with the study protocol or the ability to perform physical exercise.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Universidad Católica de Murcia
Murcia, Murcia, 30107, Spain
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