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Scientists probe immune Cells' role in scleroderma blood vessel injury

NCT ID NCT02636127

First seen May 09, 2026 · Last updated Jun 19, 2026 · Updated 7 times

Summary

This study looks at how certain immune cells, called T cells and NK cells, may harm blood vessels in people with systemic sclerosis (scleroderma). Researchers will analyze blood samples from 30 participants, including patients and healthy volunteers, to measure a protein called Fractalkine and study cell interactions. The goal is to better understand the disease, not to test a new treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Assistance Publique Hopitaux de Marseille

    Marseille, 13354, France

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this research could point toward new treatment targets for systemic sclerosis by clarifying how immune cells injure blood vessels.

What could go wrong

This is a small, observational study with only 30 participants, so findings may not apply to all patients. It is early-stage research, not a treatment trial.

Conditions

The condition(s) this trial relates to.

systemic sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.