New Triple-Drug combo aims to wipe out Hard-to-Treat leukemia
NCT ID NCT06644183
First seen Feb 17, 2026 · Last updated May 01, 2026 · Updated 5 times
Summary
This study tests whether adding a new drug called roginolisib to two standard drugs (venetoclax and rituximab) can safely make chronic lymphocytic leukemia (CLL) disappear to undetectable levels in patients whose cancer has returned or not responded to prior treatments. About 64 adults with relapsed or refractory CLL who have already tried at least two other therapies will participate. The goal is to see if this combination can achieve a deep remission, though ongoing monitoring and potential future treatment may still be needed.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02115, United States
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