Refractory leukemia
Clinical trials for Refractory leukemia explained in plain language.
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New Triple-Drug attack on tough leukemia enters human testing
Disease control Recruiting nowThis early-phase study tests whether adding a new drug called eganelisib to two standard AML medications (venetoclax and azacitidine) is safe for people with acute myeloid leukemia that has come back or not responded to treatment. About 48 adults will take part to find the best d…
Matched conditions: REFRACTORY LEUKEMIA
Phase 1 • Sponsor: Jacqueline Garcia, MD • Aim: Disease control
Last updated Aug 28, 2026 00:00 UTC
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Can a new drug duo outsmart a tough childhood leukemia?
Disease control Recruiting nowThis early-stage trial is testing whether combining two targeted drugs—olverembatinib and APG-2575—can safely and effectively treat children with a specific type of acute lymphoblastic leukemia (Ph+ ALL) that has relapsed or not responded to standard treatments. The study will fi…
Matched conditions: REFRACTORY LEUKEMIA
Phase 1 • Sponsor: Institute of Hematology & Blood Diseases Hospital, China • Aim: Disease control
Last updated Aug 28, 2026 00:00 UTC
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New drug duo targets hard-to-treat leukemias in early trial
Disease control Recruiting nowThis study tests whether combining two drugs, revumenib and mezigdomide, is safe for people with specific types of acute leukemia that have returned or not responded to prior therapy. About 52 participants aged 12 and older will take part. The goal is to find the best dose and se…
Matched conditions: REFRACTORY LEUKEMIA
Phase 1/2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
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New Three-Drug cocktail aims to outsmart tough leukemia
Disease control Recruiting nowThis study tests a new combination of three drugs—roginolisib, venetoclax, and rituximab—in people with chronic lymphocytic leukemia (CLL) that has come back or not responded to prior treatments. The goal is to see if the combination is safe and can wipe out leukemia cells more e…
Matched conditions: REFRACTORY LEUKEMIA
Phase 1/2 • Sponsor: Jennifer R. Brown, MD, PhD • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
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Experimental combo aims to help leukemia patients reach transplant
Disease control Recruiting nowThis early-phase study tests whether giving chemotherapy followed by an infusion of immune cells from a partially matched donor can help patients with relapsed or refractory leukemia get to a stem cell transplant. Only 5 participants will be enrolled to check safety and side effe…
Matched conditions: REFRACTORY LEUKEMIA
Phase 1 • Sponsor: Beijing 302 Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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New drug cocktail aims to beat back tough leukemia
Disease control Recruiting nowThis phase 2 trial is testing a combination of three drugs—venetoclax, chidamide, and azacitidine—in 30 adults with acute myeloid leukemia that has relapsed or not responded to prior treatment. The goal is to see if this combo can safely improve remission rates and survival. Part…
Matched conditions: REFRACTORY LEUKEMIA
Phase 2 • Sponsor: The First Affiliated Hospital of Xiamen University • Aim: Disease control
Last updated Jun 26, 2026 16:51 UTC