Can custom plans cut antibiotic overuse when patients leave the hospital?
NCT ID NCT06106204
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a hospital-customized plan (ROAD Home) reduces unnecessary antibiotic use at discharge for adults with pneumonia or urinary tract infections. Forty hospitals are randomly assigned to either use this tailored approach or continue their usual practices. The goal is to see if the customized plan leads to fewer days of antibiotic overuse without harming patient outcomes.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2023
- Expected to finish
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Aug 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: All Patients: * Adult patient admitted and discharged from the participating hospital and included in HMS registry * Admitted to a general care medicine service * Received any eligible antibiotic during the symptom collection window (-1 to +2 days for UTI; day 1 or 2 for pneumonia) * Immunocompetent (allowing for mild immune suppression) * Do not have a concomitant infection (e.g., antibiotic treatment for unrelated infection or prophylaxis) Specific inclusion criteria for patients with UTI: * Positive urine culture * Have normal urinary anatomy Specific inclusion criteria for patients with pneumonia: \- Discharge diagnosis of pneumonia Exclusion Criteria: All Patients: * Left against medical advice or refused medical care * Admitted on hospice * Pregnant * Unable to determine actual or expected antibiotic duration Specific exclusions for patients with UTI: \- spinal cord injury Specific exclusions for patients with pneumonia: * Cystic fibrosis * Pneumonia-related complication (e.g., empyema)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Utah
Salt Lake City, Utah, 84132, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Do all kids with pneumonia need antibiotics? study tracks Real-World decisions
- Can a digital assistant and quick tests stop unnecessary antibiotics for kids?
- Nasal swab could curb unnecessary antibiotics in pneumonia
- What lurks in urine? a biobank aims to decode Catheter-Related infections
- Can an ancient herbal formula beat antibiotics for urinary infections?
- AI could outsmart bacteria: a smarter way to choose antibiotics?