Brain device zaps seizures in Tough-to-Treat epilepsy
NCT ID NCT05147571
First seen Jun 11, 2026 · Last updated Jun 19, 2026 · Updated 3 times
Summary
This study tested a brain implant (RNS System) that delivers targeted electrical stimulation to the thalamus to reduce seizures in people aged 12 and older with drug-resistant idiopathic generalized epilepsy. The goal was to see if the device is safe and effective at cutting down generalized tonic-clonic seizures. Participants had failed at least two seizure medications before joining.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Baylor College of Medicine
Houston, Texas, 77030, United States
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Indiana University Health
Indianapolis, Indiana, 46202, United States
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Mary Hitchcock Memorial Hospital (Dartmouth)
Lebanon, New Hampshire, 03756, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Mayo Clinic - Arizona
Phoenix, Arizona, 85054, United States
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Mayo Clinic - Rochester
Rochester, Minnesota, 55902, United States
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New York University Langone
New York, New York, 10016, United States
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Nicklaus Children's Hospital
Miami, Florida, 33155, United States
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Oregon Health and Science University
Portland, Oregon, 97239, United States
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Spectrum Health Butterworth Hospital
Grand Rapids, Michigan, 48503, United States
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The University of Texas Health Science Center at Houston
Houston, Texas, 77030, United States
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Thomas Jefferson University
Philadelphia, Pennsylvania, 19107, United States
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UPMC
Pittsburgh, Pennsylvania, 15213, United States
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University of Alabama at Birmingham
Birmingham, Alabama, 35294, United States
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University of Colorado
Aurora, Colorado, 80045, United States
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University of Kansas Medical Center
Kansas City, Kansas, 66160, United States
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University of Louisville
Louisville, Kentucky, 40202, United States
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University of New Mexico
Albuquerque, New Mexico, 87131, United States
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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University of South Florida
Tampa, Florida, 33606, United States
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University of Utah Healthcare
Salt Lake City, Utah, 84132, United States
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Vanderbilt University Medical Center
Nashville, Tennessee, 37232, United States
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Washington University
St Louis, Missouri, 63110, United States
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.