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Could a single infusion boost heart healing after a massive attack?

NCT ID NCT05211401

First seen Apr 24, 2026 · Last updated Jun 09, 2026 · Updated 9 times

Summary

This study tests whether a single dose of rituximab, a drug that calms the immune system, can improve heart function six months after a severe type of heart attack called anterior STEMI. About 372 adults who have had this heart attack will receive either rituximab or a placebo. The main goal is to see if the drug helps the heart pump better, as measured by MRI.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cardiology department, Hôpital Bichat, AP-HP

    RECRUITING

    Paris, 75018, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

ST-elevation myocardial infarction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.