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New drug combo targets Hard-to-Treat cancers in early trial

NCT ID NCT01303341

First seen Nov 01, 2025 · Last updated Jun 16, 2026 · Updated 32 times

Summary

This early-phase trial tested the safety and best dose of two drugs—riluzole and sorafenib—given together to people with advanced solid tumors or melanoma that had spread and stopped responding to standard treatments. The goal was to find the highest safe dose and see if the combination could slow tumor growth. A total of 35 participants were enrolled.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Rutgers Cancer Institute of New Jersey

    New Brunswick, New Jersey, 08903, United States

Conditions

The condition(s) this trial relates to.

cancer cutaneous melanoma melanoma metastatic melanoma refractory malignant neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.