Could HIV drugs tame a rare genetic storm in kids?
NCT ID NCT02363452
First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 31 times
Summary
This study tested whether medicines usually used for HIV could help children with Aicardi-Goutières syndrome (AGS), a rare genetic disease that causes severe brain inflammation. Eleven children took reverse transcriptase inhibitors to see if the drugs could lower their interferon levels, which are too high in AGS. The goal was to control the disease, not cure it.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Hôpital Necker - Enfants Malades
Paris, 75015, France
Conditions
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