HIV drugs show promise for rare childhood brain disorder
NCT ID NCT02363452
First seen Nov 01, 2025 · Last updated Jun 15, 2026 · Updated 38 times
Summary
This study tested whether drugs normally used for HIV could help children with Aicardi-Goutières syndrome (AGS), a rare genetic disease that causes severe brain inflammation. Eleven children received reverse transcriptase inhibitors to see if the drugs could lower abnormal immune signals (interferon levels) in their blood and spinal fluid. The goal was to control the disease, not cure it, since children with AGS need lifelong management.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for AICARDI-GOUTIÈRES SYNDROME (AGS) are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Hôpital Necker - Enfants Malades
Paris, 75015, France
Conditions
Explore the condition pages connected to this study.