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New study tests Opioid-Free pain control for back surgery patients

NCT ID NCT06725680

Symptom relief Sponsor: Tanta University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compared two types of nerve blocks (retrolaminar block and erector spinae plane block) for pain control after lumbar discectomy surgery. The goal was to see which block better reduces the need for opioid painkillers and speeds up recovery. 90 adults undergoing elective back surgery were randomly assigned to receive one of the two blocks. Researchers measured how long it took for patients to need rescue pain medication and how quickly they recovered from anesthesia.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
nerve block (retrolaminar block or erector spinae plane block)
What this could lead to
If one block works better, it could offer a way to manage pain after back surgery without relying on opioids, leading to faster recovery and fewer side effects.
What could go wrong
This is a small, completed trial with only 90 participants. The results may not apply to all patients or surgeries, and nerve blocks carry risks like infection or nerve damage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

90 people

The number who actually took part.

Started

Dec 2024

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age from 18 to 65 years. * Both sexes. * American Society of Anesthesiology (ASA) physical status I-II. * Undergoing elective posterior lumbar discectomy under general anesthesia. Exclusion Criteria: * Body mass index (BMI) \>35 kg/m2. * Patients with disturbed mental status. * Allergies to the drugs used in the study. * Local infection at the puncture site. * Cardiac insufficiency. * Renal insufficiency. * Coagulopathy. * Chronic opioid use.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Enhanced recovery Erector spinae plane block Lumbar discectomy Opioid-free anesthesia Retrolaminar block

Contacts and locations

Locations

  • Tanta University

    Tanta, El-Gharbia, 31527, Egypt

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