Eye test could replace invasive heart procedure for millions
NCT ID NCT06692751
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study explores whether a simple, non-invasive eye scan (OCT-A) can diagnose microvascular angina, a heart condition affecting about 112 million people worldwide. Currently, diagnosis requires an invasive heart procedure to measure microcirculatory resistance. Researchers will compare eye scan results with the standard invasive test in 158 adults to see if the eye scan is a reliable alternative. If proven effective, this could make diagnosis faster, cheaper, and more accessible.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a quick, non-invasive eye scan to diagnose microvascular angina, replacing the current invasive heart procedure.
- What could go wrong
- This is an early observational study, not a treatment trial. It only tests if the eye scan matches the invasive test results, and may not prove useful for all patients or replace the gold standard.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 158 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2024
- Expected to finish
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Nov 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients treated at Dijon University Hospital, who received an IMR measurement as part of INOCA
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients managed at Dijon University Hospital, having had an IMR measurement as part of INOCA during a coronary angiographic examination, consecutively includible, without angiographically or functionally significant coronary epicardial lesion (FFR \< 0.80) explaining the clinical picture (= INOCA) * Person having given oral consent * Adult Exclusion Criteria: * Person not affiliated or not benefiting from a social security scheme * Person subject to a legal protection measure (curatorship, guardianship) or a safeguard of justice measure * Pregnant or breast-feeding women * An adult incapable or unable to give consent * Person with macular or retinal pathology, or severe bilateral myopia * Person with genetic or idiopathic cardiomyopathy (dilated, hypertrophic or restrictive cardiomyopathy)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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CHU Dijon Bourgogne
RECRUITINGDijon, 21000, France
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Other studies related to the condition(s) this trial covers.
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