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Red wine compound injected into gums to fight periodontitis

NCT ID NCT07397026

Disease control Sponsor: Hagar Ahmed Ali Mohammed Elzain Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial tests whether injecting resveratrol nanoparticles into the gums can improve treatment for stage III periodontitis. 48 adults will receive either the resveratrol gel, a placebo, or standard deep cleaning alone. Researchers will measure gum attachment levels and inflammatory markers after 3 months.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
resveratrol loaded nanoparticles
What this could lead to
If it works, this could point toward a new gum disease treatment that reduces inflammation and improves healing.
What could go wrong
This is a very early phase 1 trial with only 48 people. It is too small to prove effectiveness, and resveratrol may not work better than standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 1

The first testing in people. Mainly checks safety and dose, usually in a small group.

Participants

48 people

The number who actually took part.

Started

Aug 2025

Expected to finish

Apr 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

25 to 55 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Adult patient 25-55 years. 2. Presence of ≥20 teeth. 3. PPD \>3\&≤5 mm. 4. The patients are in good systemic health. 5. Patients have not received any periodontal surgery in the areas that will be assessed in the last 6 months Exclusion Criteria: 1. Patients with systemic diseases. 2. Pregnant and lactating women. 3. Heavy Smokers and tobacco chewers. 4. Patients do not follow oral hygiene measures. 5. Patients with a known or suspected allergy to any material used in the study.

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Conditions

The condition(s) this trial relates to.

periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Periodontitis stage III

Contacts and locations

Locations

  • Faculty of dentistry , Mansoura university

    Al Mansurah, DK, 35516, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.