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Less fluid, less harm? new trial challenges standard sepsis care

NCT ID NCT06140147

First seen Nov 01, 2025 · Last updated May 19, 2026 · Updated 26 times

Summary

This study compares a strategy that limits non-resuscitation fluids to usual care in adults with septic shock. The goal is to see if a restrictive approach reduces death and serious complications. About 1,850 participants will be enrolled in ICUs across multiple centers.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Danderyd Hospital

    RECRUITING

    Danderyd, Sweden

  • Falun Hospital

    RECRUITING

    Falun, Sweden

  • Halmstad Hospital

    RECRUITING

    Halmstad, Sweden

  • Helsingborg Hospital

    RECRUITING

    Helsingborg, Sweden

  • Helsinki University Hospital

    RECRUITING

    Helsinki, Finland

  • Kuopio University Hospital

    NOT_YET_RECRUITING

    Kuopio, Finland

  • Malar Hospital

    RECRUITING

    Eskilstuna, Sweden

  • Norrtälje Hospital

    RECRUITING

    Norrtälje, Sweden

  • Sahlgrenska University Hospital

    RECRUITING

    Gothenburg, Sweden

  • Skåne University Hospital, Lund

    RECRUITING

    Lund, Sweden

  • Skåne University Hospital, Malmö

    RECRUITING

    Malmö, Sweden

  • Stockholm South General Hospital (SÖS)

    RECRUITING

    Stockholm, Sweden

  • Södertälje Hospital

    NOT_YET_RECRUITING

    Södertälje, Sweden

  • Tampere University Hospital

    NOT_YET_RECRUITING

    Tampere, Finland

  • Turku University Hospital

    NOT_YET_RECRUITING

    Turku, Finland

  • University Hospital of Umeå

    RECRUITING

    Umeå, Sweden

  • University Hospital of Wales

    NOT_YET_RECRUITING

    Cardiff, United Kingdom

  • Uppsala University Hospital

    RECRUITING

    Uppsala, Sweden

  • Varberg Hospital

    RECRUITING

    Varberg, Sweden

  • Örebro University Hospital

    RECRUITING

    Örebro, Sweden

  • Östersund Hospital

    RECRUITING

    Östersund, Sweden

  • Östra Hospital

    RECRUITING

    Gothenburg, Sweden

Conditions

Explore the condition pages connected to this study.