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Lifting weights may boost fat metabolism in older women at risk for diabetes

NCT ID NCT05351476

Knowledge-focused Sponsor: Florida State University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how resistance training (like lifting weights) affects fat breakdown in obese postmenopausal women who also have prediabetes. Researchers want to see if this type of exercise can improve how the body uses fat, which might help prevent type 2 diabetes. The study involves 120 women who will do resistance training for 12 weeks, and their fat metabolism will be measured before and after.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 120 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2022

Expected to finish

Apr 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 to 75 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Women * Postmenopausal (50-75 yrs.) * Obese (BMI 30-50 kg/m2) * Prediabetes (HbA1c 5.7 - 6.4% or fasting blood glucose 100 to 125 mg/dL, or 2hr OGTT blood glucose 140 to 199 mg/dL) * Sedentary (not performing purposeful exercise training more than 20 minutes per day twice a week) * Non-smokers * No hormone replacement therapy for at least the past two years. Exclusion Criteria: * Engaging in purposeful resistance training or endurance training (\> 20min/day, \> 2 days/week) * Resting blood pressure above 140 mmHg systolic or 90 mmHg diastolic * Type 1 or type 2 diabetes * Medical problems in which exercise is contraindicated, such as chronic infections * History of, or currently presentation with, cancer, cardiovascular or respiratory disease * Uncontrolled thyroid dysfunction, liver or renal dysfunction * Taking any medication affecting lipid metabolism * Musculoskeletal disease or injury that would otherwise prevent engagement in resistance and endurance training * Smokers and those with diagnosed eating disorders

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder prediabetes syndrome type 2 diabetes mellitus prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Obesity Postmenopausal symptoms Prediabetic state

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Florida State University

    RECRUITING

    Tallahassee, Florida, 32306, United States

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