Popular Weight-Loss drugs may leave food in stomach despite fasting
NCT ID NCT06500143
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether GLP-1 medications (used for diabetes and weight loss) increase the risk of having food or liquid in the stomach before surgery, even after the recommended fasting period. Researchers used a quick ultrasound to check stomach contents in 94 adults scheduled for elective surgery. The goal was to see if these drugs might make fasting less effective, potentially raising safety concerns.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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94 people
The number who actually took part.
- Started
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Oct 2024
- Finished
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Feb 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult population undergoing elective surgery
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * American Society of Anesthesiologists (ASA) class 1-4 patients * Age ≥ 18 years old * Fasted state (2 hours for clear liquids, 6 hours for solids) * Elective surgery * Last dose of once-weekly semaglutide or dulaglutide 7 days or more before surgery (for GLP-1RA group) Exclusion Criteria: * Last dose of GLP-1RA less than 7 days before surgery * Inability to lay on the right-side for ultrasound * Pregnancy * History of gastric surgery or large hiatal hernia
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CIUSSS de l'Est de l'Ile de Montréal
Montreal, Quebec, H1T2M4, Canada
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