Brain zaps may restore aging vision, early study hints
NCT ID NCT07208318
First seen Jun 27, 2026 · Last updated Jul 17, 2026 · Updated 2 times
Summary
This study tests whether age-related vision problems are caused by disrupted brain signals and if a noninvasive brain stimulation technique can fix them. Researchers will use brain scans and personalized electrical stimulation in 240 older adults to try to improve contrast sensitivity and 3D motion perception. The goal is to understand and potentially treat visual decline in aging, with possible implications for Alzheimer's disease.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Early phase 1
The earliest testing in people: a first look at safety, in a very small group.
- Participants
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About 240 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2026
- Expected to finish
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Aug 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * 18+ years of age or older * normal or corrected-to-normal visual acuity, color vision, and stereo vision Exclusion Criteria: * not pregnant, * no metal implants in head, * no implanted electronic devices, * no history of neurological problems or head injury, * no skin sensitivity, * no claustrophobia, * no dementia (normal Mini Mental State Examination between 24-30; Montreal Cognitive Assessment \> 25) * no depression (normal Beck Depression Inventory II \<13; Geriatric Depression Scale \< 10) * no ophthalmological diseases (e.g., strabismus, glaucoma, cataract, macular degeneration) * no history of psychosis * no cognitive deficits (MMSE score\>24; MoCA\>25) * cannot be taking any psychoactive medication.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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111 Cummington Mall, Boston University
RECRUITINGBoston, Massachusetts, 02215, United States
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