Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Could a collagen patch help heal hip cartilage better than standard surgery?

NCT ID NCT05402072

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This pilot study compares two surgical techniques for repairing damaged hip cartilage in 40 people aged 18 to 55. One group receives standard microfracture surgery, while the other gets an enhanced procedure called AMIC, which uses a collagen patch to protect the repair site. Researchers will measure hip function, pain, and cartilage healing over two years to see if the patch leads to better outcomes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
collagen matrix (Chondro-Gide®) used in the AMIC procedure
What this could lead to
If successful, this could provide a better surgical option for repairing hip cartilage damage, potentially improving long-term hip function and reducing pain.
What could go wrong
This is a small, early-phase pilot study with only 40 participants, so results may not apply to everyone. The procedure is still experimental and may not prove better than the standard microfracture technique.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 1

The first testing in people. Mainly checks safety and dose, usually in a small group.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2023

Expected to finish

Jan 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 55 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. All patients aged 18-55 years 2. Hip pain lasting 6 months or more with no relief from documented non-operative modalities 3. Focal articular cartilage defects of the acetabulum on MRI, confirmed to be full thickness (International Cartilage Regeneration and Joint Preservation Society (ICRS) grade 3 or 4) during arthroscopic examination 4. Focal acetabular articular cartilage lesions measuring between 3 cm2 and 25 cm2 on MRI and confirmed on arthroscopic examination 5. Patient agrees to participate in the study-specific postoperative rehabilitation protocol 6. Patient can speak, read, and understand the language of the site 7. Patient has provided informed consent Exclusion Criteria: 1. Cartilage defects of the femoral head 2. Previous surgery on the study hip 3. Traumatic chondral injury of the hip from a single event 4. Presence of advanced osteoarthritis (Tonnis grade 3) or any other acute or chronic inflammatory joint disease 5. Known hypersensitivity or allergy to porcine collagen 6. Acute or chronic infection at the surgical site 7. Evidence of hip dysplasia (i.e., lateral centre edge angle \< 20˚) 8. Evidence of acetabular over coverage such as coxa profunda or coxa protrusion 9. Immunosuppressive or anti-proliferative medication use 10. Chronic pain syndromes 11. Significant medical co-morbidities (requiring assistance for activities of daily living (ADLs)) 12. History of paediatric hip disease 13. Uncontrolled diabetes 14. Contraindications to MRI imaging (e.g. claustrophobia) 15. Patient is involved in ongoing legal or workplace claims 16. Patient is incarcerated 17. Patient is pregnant or breastfeeding 18. Patient who will likely have problems, in the judgement of the investigator, with maintaining follow-up 19. Any other reason(s) the investigator feels is relevant for excluding the patient

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Articular cartilage defect are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • McMaster University

    RECRUITING

    Hamilton, Ontario, L8N3Z5, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.