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No-Narcotic pain relief after hip surgery shows promise

NCT ID NCT05076110

Symptom relief Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a combination of non-narcotic pain relievers—ibuprofen, gabapentin, acetaminophen, and methocarbamol—after hip arthroscopy. 86 adults participated to see if this regimen could control pain without using opioids. The goal was to find a safer way to manage post-surgery pain.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a combination of ibuprofen, gabapentin, acetaminophen, and methocarbamol
What this could lead to
If successful, this could offer a way to manage pain after hip surgery without using narcotics, reducing the risk of addiction.
What could go wrong
This is a small, single-center study with 86 participants, so results may not apply to everyone. The regimen may not control pain as well as narcotics for some patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

86 people

The number who actually took part.

Started

Apr 2022

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

16 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: • Scheduled for a primary Hip Arthroscopy at Mayo Clinic (Rochester, MN) Exclusion Criteria: * medical history of known allergies or intolerance to allergies or intolerance to Motrin, Gabapentin, Tylenol, dexamethasone, tramadol, or Robaxin. * Substantial alcohol or drug abuse. * History of narcotics within 6 months of surgery. * Pregnancy. * Renal impairment. * Peptic ulcer disease. * GI bleeding.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hip arthroscopy

Contacts and locations

Locations

  • Mayo clinic

    Rochester, Minnesota, 55401, United States

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