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Simple cuff trick may shield heart during surgery

NCT ID NCT02427867

First seen May 15, 2026 · Last updated May 25, 2026 · Updated 3 times

Summary

This study tests whether briefly inflating a blood-pressure cuff on the arm before surgery can reduce heart damage in high-risk patients. Over 1,200 adults undergoing non-cardiac surgery will be randomly assigned to receive the cuff procedure or a sham. The goal is to see if this simple, low-cost technique lowers cardiac troponin levels, a marker of heart injury.

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Contacts and locations

Locations

  • A.O.U. Pisana

    Pisa, Italy

  • Astana Medical University

    Astana, 010000, Kazakhstan

  • Azienda Ospedaliero Universitaria Careggi

    Florence, 50139, Italy

  • Azienda Sanitaria Universitaria Friuli Centrale "Santa Maria della Misericordia"

    Udine, 33100, Italy

  • Azienda Universitaria Ospedaliero Pisana

    Pisa, 56100, Italy

  • E.O. Ospedali Galliera

    Genova, 16128, Italy

  • Fondazione IRCCS. Istituto Neurologico Carlo Besta

    Milan, 20133, Italy

  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS

    Rome, 00136, Italy

  • Fondazione Policlinico Universitario Campus Bio-Medico di Roma

    Rome, 00128, Italy

  • Fundación Cardioinfantil-Instituto de Cardiología

    Bogotá, 110131, Colombia

  • Humanitas Clinical Institute

    Rozzano, Lombardy, 20100, Italy

  • I.M. Sechenov First Moscow State Medical

    Moscow, Russia

  • IRCCS San Raffaele Scientific Institute

    Milan, 20132, Italy

  • Institute of Cardiovascular Diseases "Dedinje"

    Belgrade, Serbia

  • Loginov Moscow Clinical Scientific Center

    Moscow, 111123, Russia

  • National University Hospital

    Singapore, 119074, Singapore

  • Oncological Center No. 1 of the S. S. Yudin City Clinical Hospital of the Moscow Department of Health

    Moscow, 117152, Russia

  • Ospedale Cardinal Massaia

    Asti, 14100, Italy

  • Ospedale Regionale di Lugano

    Lugano, Switzerland

  • Saint-Petersburg State University Hospital

    Saint Petersburg, Russia

  • ULSS 4 Veneto Orientale, Ospedale di San Donà di Piave

    San Donà di Piave, 30027, Italy

  • University Hospital Centre Zagreb

    Zagreb, 10000, Croatia

  • Università degli studi della Campania Luigi Vanvitelli

    Naples, 80138, Italy

  • V.Negovsky Reanimatolgy Research Institute

    Moscow, Russia

  • Valle Olona Po hospital

    Busto Arsizio, Varese, Italy

  • Xijing Hospital

    Xi'an, 710032, China

Conditions

Explore the condition pages connected to this study.