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Arm cuff trick may shield heart during surgery

NCT ID NCT05733208

Prevention Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a simple, non-invasive technique called remote ischemic preconditioning (RIPC) can prevent heart injury in patients at high risk for heart problems who are undergoing major abdominal surgery. RIPC involves briefly inflating a blood pressure cuff on the arm to restrict blood flow, then releasing it, which may signal the heart to better handle stress. The trial includes 766 participants and compares RIPC to a sham procedure to see if it reduces heart damage after surgery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 766 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2023

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

45 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria 1. Patients at high clinical risk for cardiovascular events; 2. Patients scheduled to undergo major abdominal surgery. Exclusion criteria 1. Immediate or urgent surgery or surgery where there is insufficient time to perform RIPC. 2. Abdominal vascular surgery, such as surgery for abdominal aortic aneurysm 3. Experience of conditions precluding the use of RIPC in both arms 4. Patients who are being treated with drugs, such as sulphonamide or nicorandil 5. With contraindications for anaesthetic regimes required in this trial.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Myocardial injury Non-cardiac surgery Remote ischemic preconditioning

Contacts and locations

Locations

  • The Sixth Affiliated Hospital, Sun Yat-sen University

    Guangzhou, Guangdong, 510655, China

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