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Could a blood pressure cuff boost stroke recovery? trial tests the idea

NCT ID NCT06823128

Disease control Sponsor: The First Affiliated Hospital of University of Science and Technology of China Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether repeatedly inflating and deflating a blood pressure cuff on the arm (remote ischemic conditioning) could improve recovery in 458 people who had a severe stroke caused by a blocked artery in the brain. The goal was to see if this simple, non-drug treatment could reduce disability 90 days later. The study was terminated early, so results are limited.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

458 people

The number who actually took part.

Started

Apr 2025

Finished

Feb 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age is 18 years old or above. 2. Severe stenosis (70% - 99%) or occlusion of anterior intracranial circulation vessels, mainly including the intracranial segment of the internal carotid artery, middle cerebral artery (M1, M2) and anterior cerebral artery (A1, A2), which is confirmed by digital subtraction angiography (DSA), computed tomography angiography (CTA) or magnetic resonance angiography (MRA). 3. Patients with clinically diagnosed acute ischemic stroke who received remote ischemic treatment within 72 hours after the onset. 4. The NIHSS score ranges from 4 to 24. 5. The mRS score before stroke is less than or equal to 1. 6. informed consent. Exclusion Criteria: 1. Patients with vessel recanalization after mechanical thrombectomy (TICI grade ≥ 2b). 2. Patients planning to receive intracranial endovascular treatment within 3 months. 3. Patients diagnosed with acute posterior circulation cerebral infarction. 4. Symptoms caused by non - culprit vessels. 5. Ipsilateral extracranial vessel stenosis ≥ 70%. 6. Systolic blood pressure \> 185 mmHg or diastolic blood pressure \> 110 mmHg, and uncontrollable by antihypertensive drugs. 7. Intracranial tumors, arteriovenous malformations or aneurysms. 8. Cerebral venous thrombosis or stenosis. 9. Severe coagulation abnormalities. 10. Any contraindications to remote ischemic conditioning: severe soft tissue injury, fracture or vascular injury of the upper limb, perivascular lesions of the distal upper limb, etc. 11. Patients with any serious diseases and a life expectancy of less than 1 year. 12. Patients who participated in other clinical trials within 3 months before enrollment or are currently participating in other clinical trials. 13. Patients who cannot be followed up (such as those without a fixed residence, overseas patients, etc.). 14. Pregnant or lactating women. 15. Patients who have previously received remote ischemic treatment or similar treatments. 16. Patients whom the researchers consider unsuitable for this clinical study.

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Conditions

The condition(s) this trial relates to.

Bites and Stings Constriction, Pathologic ischemic stroke

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute ischemic stroke

Contacts and locations

Locations

  • The First Affiliated Hospital of University of Science and Technology of China

    Hefei, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.