Can remote exercise and weight loss boost heart failure Patients' stamina?
NCT ID NCT07223242
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 42 times
Summary
This study tests whether a tailored, home-based exercise program (with or without weight loss medications) can improve exercise capacity and quality of life in 120 adults with heart failure with preserved ejection fraction (HFpEF). Participants will follow exercise videos and meet weekly with a coach. The goal is to find a practical, accessible way to help people with HFpEF feel better and be more active.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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University of Texas Southwestern Medical Center
RECRUITINGDallas, Texas, 75209, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
exercise training (moderate-intensity continuous training and resistance training) and weight loss medications (semaglutide or tirzepatide)
What this could lead to
If successful, this could offer a practical, home-based exercise program to help people with HFpEF feel better, move more easily, and improve their daily life.
What could go wrong
This is a mid-stage trial with only 120 participants, so results may not apply to everyone. The exercise program is remote, so adherence and effectiveness may vary.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.