Scientists test best way to combine two common anesthetics
NCT ID NCT07620782
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how two drugs used for general anesthesia—remimazolam and sevoflurane—interact with each other. Researchers will give 80 adults having laparoscopic surgery different combinations of these drugs and measure their brain activity. The goal is to find the best way to use them together for safer anesthesia.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- remimazolam and sevoflurane
- What this could lead to
- If successful, this study could help doctors better understand how to combine these two anesthetics for safer and more predictable anesthesia during surgery.
- What could go wrong
- This is a small, early-phase study focused on modeling drug interactions, not on treating a disease. The results may not directly change clinical practice.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 80 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2026
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 20 to 80 years * Scheduled for elective surgery under general anesthesia at Pusan National University Yangsan Hospital * American Society of Anesthesiologists (ASA) physical status I or II * Able to provide written informed consent Exclusion Criteria: * Known allergy to remimazolam or sevoflurane * Renal, hepatic, neuromuscular, or neurological disease * Use of medications affecting the central nervous system * Chronic psychoactive drug use * Ischemic heart disease * Pregnant women
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Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Pusan National University Yangsan Hospital
RECRUITINGYangsan, 50612, South Korea
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