New combo therapy shows promise for tough bone cancer
NCT ID NCT04803877
First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 33 times
Summary
This study tests a combination of two drugs (regorafenib and nivolumab) in people with osteosarcoma, a type of bone cancer, that has returned or not responded to prior treatment. The goal is to see if this combination can stop the cancer from growing for at least 4 months longer than historical results with regorafenib alone. About 48 participants aged 5 and older are enrolled.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Children's Hospital of Los Angeles
Los Angeles, California, 90027, United States
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Cincinnati Children's
Cincinnati, Ohio, 45229, United States
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Johns Hopkins
Baltimore, Maryland, 21287, United States
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Oregon Health and Sciences University
Portland, Oregon, 97239, United States
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UT Southwestern Medical Center
Dallas, Texas, 75390, United States
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University of Miami
Miami, Florida, 33136, United States
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University of Michigan
Ann Arbor, Michigan, 48109, United States
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University of Minnesota
Minneapolis, Minnesota, 55455, United States
Conditions
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