Can nicotine help protect kids from smoke?
NCT ID NCT01896518
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether giving nicotine products to caregivers who smoke and don't want to quit can reduce the smoke their children breathe. 74 caregivers and their kids took part. The main goal was to measure changes in kids' exposure to smoke using a saliva test.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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74 people
The number who actually took part.
- Started
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Nov 2012
- Finished
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Dec 2014
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: In order to be included in the study, participants must: 1. be the primary caregiver(defined as a person who spends the most time with the child and spends a minimum of 4 hours per day in the presence of the child) of a child between the ages of 3-11 (if caregiver has more \> 1 child between 3-11 years, we will include the youngest), 2. smoke at least 10 cigarettes per day for the past year, 3. indicate that they smoke around their child or in the car or home at least one time per week\], 4. have no intention of quitting smoking in the next 12-weeks, 5. aged 18-65 years, 6. be fluent in English, 7. have no recent history of cardiovascular distress that may contraindicate medicinal nicotine lozenge use (heart attack in the past year, arrhythmia, uncontrolled hypertension), 8. not currently pregnant, planning to become pregnant, or breastfeeding, 9. do not use non-cigarette tobacco (cigars, chewing tobacco) 10. have no prior use of any potential reduced exposure product, 11. have no major psychiatric impairment, including psychosis, suicidality, and/or any current alcohol/drug abuse or dependence Exclusion Criteria: Does not meet all of the requirements of inclusion criteria
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The Children's Hospital at OU Medical Center
Oklahoma City, Oklahoma, 73104, United States
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