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EHR nudges aim to curb dangerous pill overload in seniors

NCT ID NCT05656560

Disease control Sponsor: Northwestern University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether simple electronic alerts in doctors' charts can reduce high-risk polypharmacy—taking multiple medications that may interact dangerously—in older adults, especially those with dementia. About 786 patients from primary care clinics will be included. Doctors receive either a commitment nudge, a justification nudge, both, or none, and the study tracks changes in medication safety over 18 months.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
behavioral nudges (commitment and justification prompts in electronic health records)
What this could lead to
If successful, this could give doctors a simple, low-cost tool to reduce dangerous medication combinations in older adults, potentially preventing falls and drug reactions.
What could go wrong
This is a pragmatic trial testing behavioral prompts, not a new drug. The effect may be small, and results might not apply to all clinics or patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

786 people

The number who actually took part.

Started

Jun 2023

Expected to finish

May 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Northwestern Medicine or UPMC primary care clinic: Internal Medicine, Family Medicine, or General Practice or Geriatrics Exclusion Criteria: * None

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Polypharmacy

Contacts and locations

Locations

  • Northwestern Medicine

    Chicago, Illinois, 60611, United States

  • UPMC

    Pittsburgh, Pennsylvania, 15213, United States

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