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New program aims to cut dangerous drug combinations in seniors

NCT ID NCT03689049

Knowledge-focused Sponsor: University of Toronto Practice Based Research Network Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a program called SPIDER that helps family doctors, nurses, and pharmacists work together to reduce risky prescriptions in older adults taking 10 or more medications. The program uses data from electronic medical records and coaching sessions to identify and reduce four types of potentially harmful drugs. Researchers will enroll 104 patients across Canada to see if the program works and is worth the cost.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
SPIDER program (learning collaboratives and quality coaching)
What this could lead to
If it works, this could provide a practical, data-driven method for family doctors to reduce harmful medications in older patients.
What could go wrong
This is a small feasibility study, not a large trial. The program may not work in all clinics or may be too costly to scale.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 104 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2018

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

65 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria: 1. At practice level: a) contributes EMR data to the repository of a Practice Based Research Network (PBRN) that participates in CPCSSN; and b) includes a primary care provider (PCP) who consents to participate and lead the practice QI team. 2. At PCP level: a) practices comprehensive family medicine in an office setting (academic or non-academic); and b) consents to participate and allow the research staff to provide study information to their eligible patients. 3. At patient level: a) 65 years or older; b) has at least one office visit during the past 2 years; and c) has received ten or more different prescription medications (as indicated in the EMR) in the past year. Exclusion criteria: 1. At practice level: a) Does not use EMR; b) does not contributes EMR data to the repository of a PBRN that participates in CPCSSN; or c) none of the PCPs at the practice consents to participate. 2. At PCP level: a) does not practice comprehensive family medicine in an office setting; b) does not consent to participate; c) does not allow the research staff to contact or provide study information to their eligible patients; or d) has left the practice. 3. At patient level: a) younger than 65 years of age; b) has not visited a practice over the past 2 years; or c) has received fewer than ten different prescription medications in the past year. (Note: * PBRN: Practice Based Research Network; * CPCSSN: the Canadian Primary Care Sentinel Surveillance Network)

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Aged Electronic health records Inappropriate prescribing Polypharmacy Primary health care Quality improvement

Contacts and locations

Locations

  • Atlantic Practice Based Research Network (APBRN)

    St. John's, Newfoundland and Labrador, A1B 3V6, Canada

  • British Columbia node of the pan-Canadian CPCSSN (BC-CPCSSN)

    Vancouver, British Columbia, V6T 2B5, Canada

  • Manitoba Primary Care Research Network (MaPCReN)

    Winnipeg, Manitoba, R3E 0T6, Canada

  • Maritime Family Practice Research Network (MaRNet-FP)

    Halifax, Nova Scotia, B3H 2E2, Canada

  • Northern Alberta Primary Care Research Network (NAPCReN)

    Edmonton, Alberta, T6G 2T4, Canada

  • Ottawa Practice Enhancement Network (OPEN )

    Ottawa, Ontario, K1R 7G5, Canada

  • Réseau de recherche en soins primaires de l'Université de Montréal (RRSPUM)

    Laval, Quebec, H7M 3L9, Canada

  • Southern Alberta Primary Care Research Network (SAPCReN)

    Calgary, Alberta, T2N 4N1, Canada

  • University of Toronto Practice Based Research Network

    Toronto, Ontario, M5G 1V7, Canada

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