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Could deprescribing prevent dementia? new study investigates

NCT ID NCT04270474

First seen May 02, 2026 · Last updated May 23, 2026 · Updated 7 times

Summary

This study looks at whether carefully stopping certain medications (called anticholinergics) can help prevent dementia in older adults. Researchers are following 344 people aged 65 and older who take these drugs, comparing those who get a deprescribing plan with those who receive usual care. The goal is to see if reducing these medications improves thinking, memory, and quality of life over two years.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Community Health Network Foundation, Inc.

    Indianapolis, Indiana, 46256, United States

  • Indiana University Health

    Indianapolis, Indiana, 46202, United States

Conditions

Explore the condition pages connected to this study.