Could a lower HIV drug dose work just as well?

This study tested whether reducing the daily dose of the HIV drug darunavir from 800 mg to 400 mg could keep the virus suppressed in 100 adults who already had undetectable viral loads. Participants were on a stable regimen including darunavir and two other drugs. The goal was to see if the lower dose maintained viral suppression below 50 copies/mL at 48 weeks. This is a disease control study, not a cure, as lifelong medication is still needed.