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New drug cocktail before surgery shows promise against advanced rectal cancer

NCT ID NCT07281157

First seen Jan 04, 2026 · Last updated Apr 28, 2026 · Updated 19 times

Summary

This study is testing whether a combination of three drugs (irinotecan liposome, capecitabine, and enlansubemab) given with a short course of radiation before surgery can shrink or eliminate tumors in people with locally advanced rectal cancer. About 30 adults aged 18-75 with stage T3-4 or node-positive rectal cancer will participate. The main goal is to see if the cancer completely disappears after treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Tianjin Medical University Cancer Institute & Hospital

    RECRUITING

    Tianjin, Tianjin Municipality, 300000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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